It was not an April Fools joke: Santana will head to Las Vegas this May. The seminal guitarist and his road band will host a multi-year run at Las Vegas The Joint At Hard Rock Hotel & Casino that is being billed as Sin Citys first rock residency show. Carlos Santana and his band will play approximately 36 shows per year at the 4,000-seat venue, beginning Wednesday, May 27. Supernatural Santana: A Trip Through the Hits promises to include a nostalgic collection of touchstone tracks reaching back as far as the first charting single Jingo in 1969.’ According to reports, Madonna’s production team is working on the show’s stage design.

The Joint will be the only place west of the Mississippi fans can see Santana perform through 2010 (not counting the occasional sit in). Santana will continue to perform in other markets, however and is scheduled to commence a European tour at Bucharest, Romanias B’estfest Festival on July 4.